6
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6490 | Epothilone A | epothile,Epo A | Apoptosis , Microtubule Associated |
Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM. | |||
T6075 | Epothilone B | Patupilone,EPO 906 | Apoptosis , Microtubule Associated , Antibiotic , Antifungal |
Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum. Similar to paclitaxel, patupilone induces microtubule polymerization and stabilizes microtubules against depolymerization conditi... | |||
T2445 | FG-2216 | YM-311,FG2216,FG 2216 | HIF/HIF Prolyl-Hydroxylase |
FG-2216 (YM-311) is a potent HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme (IC50: 3.9 uM); orally bioavailable and induced reversible and significant Epo induction in vivo. | |||
TP1195 | Cibinetide | ARA290 | Others |
Cibinetide (ARA290) is a nonerythropoietic peptide engineered from erythropoietin,, and used for neurological disease treatment. | |||
T82456 | EPO mimetic peptide-1 | EMP-1 | |
EPO Mimetic Peptide-1 (EMP-1) is a 20 amino acid peptide that promotes cell proliferation, modulates the cell cycle, and stimulates reticulocyte production in vivo [1]. | |||
T79797 | PHD-IN-1 | HIF/HIF Prolyl-Hydroxylase | |
PHD-IN-1 (compound 80) serves as a potent PHD2 inhibitor, exhibiting an IC50 value of ≤5 nM. It demonstrates EC50 values of 2.5 μM in EPO Elisa assays within both Caco2-HIF1a-HiBiT-clone-1 and Hep3B cell lines [1]. |